Figure 3From: Viral fitness cost prevents HIV-1 from evading dolutegravir drug pressureEffects of the H51Y and R263K mutations on HIV integration. Integrated HIV DNA was quantified by qPCR in primary human PBMCs infected with wild-type virus and with viruses containing the H51Y, R263K, and H51Y/R263K mutations for 72h. DNA was normalized for β-globin gene content relative to the the signal detected for wild-type virus, arbitrarily set at 100%. Error bars indicate ± s.e.m.Back to article page