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Table 4 Summary of point and indel errors arising during PCR and 454 sequencing

From: Analysis of 454 sequencing error rate, error sources, and artifact recombination for detection of Low-frequency drug resistance mutations in HIV-1 DNA

 

Point mutation %

Indel mutation

 

Minimal

Maximal

Mean

Std

Minimal

Maximal

Mean

Std

Run1

0.02

1.36

0.15

0.14

0.002

49.99

0.51

4.16

Run2 amplified

0.008

1.06

0.12

0.16

0.002

12.18

0.25

1.10

Run2 cloned (MID2)

0.001

0.72

0.02

0.06

0.001

20.84

0.25

1.14