Figure 3

Transmitter envelope viruses replicate significantly better than recipient envelope viruses in CD4+ T cells. (A) Recipient relative to transmitter envelope virus replication area under the curve (AUC) among CD4+ T cells from blood donation volunteer 1 (circle), 2 (square), 3 (triangle), and 4 (star). X-axis shows the couple’s ID. The dotted line at a ratio of 1 separates instances when the recipient envelope viruses replicated to a greater extent than the transmitter envelope viruses (> 1) or vice-versa (< 1). (B) Correlation between interval from estimated infection to sampling and recipient to transmitter CD4+ T cell replication AUC ratio. Graph also shows the correlation coefficient with a Spearman rank correlation p - value.