Figure 3
From: Protease inhibitors effectively block cell-to-cell spread of HIV-1 between T cells
Protease Inhibitors effectively block cell-to-cell transfer from HIV-1 infected primary T cells: HIV-1 infected primary CD4+ T cells (donor cells) were incubated with LPV (14 μM) for 24 h and mixed with uninfected Jurkat cells (targets) and cell-to-cell spread was quantified by qPCR as described in Figure 1. A representative of two independent experiments performed with two different donors is shown. Data are the mean and error bar represent the SD, **** P < 0.0001, *** P < 0.001, two-way ANOVA with Bonferroni post test.