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Figure 3 | Retrovirology

Figure 3

From: Transcriptional profiling reveals molecular signatures associated with HIV permissiveness in Th1Th17 cells and identifies Peroxisome Proliferator-Activated Receptor Gammaas an intrinsic negative regulator of viral replication

Figure 3

GO classification of differentially expressed genes in Th1Th17 vs. Th1 cells. Differentially expressed genes (p < 0.05, FC cut off 1.3) in Th1Th17 vs. Th1 were classified based on their biological functions using GO as follows: Adhesion (A), Cytokines/Chemokines (B), Inflammatory responses (C), Immune responses (D), Differentiation (E), Transcription (F), and Signal transduction (G). The corresponding heat maps were generated using the R programming language and the pheatmap and ggplot2 libraries (R Core Team). For each heat map, genes expressed at higher and lower levels in Th1Th17 vs. Th1 are represented in red and blue, respectively. Results correspond to matched Th1Th17 and Th1 subsets described in Figure 2.

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