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Figure 7 | Retrovirology

Figure 7

From: HIV-1-associated PKA acts as a cofactor for genome reverse transcription

Figure 7

Contribution of virus-associated PKA activity in endogenous reverse transcription. NL4.3 viruses were subjected to ERT experiments run in the presence of dNTPs and increasing concentrations of H89 (A) or Myr-PKI (B). For each reaction, nucleic acids were extracted and (-)ssDBNA production was quantified by qPCR amplification. DNA levels detected in ERT reactions performed in the presence of nevirapine are indicated by a dotted line. Data are mean values of duplicate experiments and are expressed as a percentage of WT conditions.

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