Figure 4
From: Differential inhibition of LINE1 and LINE2 retrotransposition by vertebrate AID/APOBEC proteins
DNA editing activities of various AID and APOBEC proteins determined with the E. coli mutator assay. (A, C) Frequencies of rifampicin resistant (RifR) colonies in KL16 (ung+) E. coli cultures carrying human AID (hAID), zebrafish AID (zfAID), zebrafish A2a (zfA2a), zebrafish A2b (zfA2b) and lizard A1 variants F3 (lizA1F3) and F8 (lizA1F8) expression plasmids or the vector as control. (B, D) Mutation frequencies of BW310 (ung-1) E. coli cultures expressing AID/APOBEC proteins or a vector control as in A and C, but note the larger scale on the y-axis. Each point represents the mutation frequency of an independent overnight culture. Median mutation frequencies are indicated.