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Table 1 Comparison of marker mean fluorescent intensity on Do4787, Do3528, and Do9432 macrophages

From: A consensus surface activation marker signature is partially dependent on human immunodeficiency virus type 1 Nef expression within productively infected macrophages

Marker CD14    CD69    CD86    CD68   
Sample Mock HIV-GFP+ Bystander Mock HIV-GFP+ Bystander Mock HIV-GFP+ Bystander Mock HIV-GFP+ Bystander
Day 0 Avg 39.12 (n = 8) n/a n/a 48.21 n/a n/a 68.57 n/a n/a 68.66 n/a n/a
Day 0 SD 32.61 n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a n/a
Significance p < .05           n/a   
Day 7 Avg 59.81 (n = 9) 39.15 32.28 54.49 44.38 29.24 53.85 (n = 4) 30.59 43.45 47.69 20.95 16.22
Day 7 SD 42.48 19.45 9.19 n/a n/a 11.01 68.1 24.03 18.78 3.555 n/a n/a
Significance p < .05     n/a n/a n/a       
Day 14 Avg 52.98 (n = 18) 49.2 37.42 56.03 (n = 3) 49.41 33.29 86.91 (n = 3) 49.99 34.05 71.86 67.91 53.59
Day 14 SD 24.77 20.93 8.28 21.36 22.33 15.44 61.77 17.57 8.67 2.44 22.27 8.62
Significance p < .05   *           
Day 21–28 Avg 74.56 (n = 17) 66.23 52.9 63.53 (n = 6) 59.91 72.67 114.32 (n = 9) 74.33 33.49 97.86 128.51 96.52
Day 21–28 SD 28.54 24.59 15.98 32.27 32.81 44.41 71.02 26.29 25.85 54.05 43.18 79.6
Significance p < .05         *     
Day 29–35 Avg 66.64 (n = 10) 50.81 35.91 50.76 (n = 3) 46.81 41.67 112.29 (n = 4) 86.41 60.91 62.45 100.37 66.34
Day 29–35 SD 23.99 24.43 12.39 19.88 16.75 12.28 57.61 34.87 7.52 36.22 82.29 12.36
Significance p < .05             
  1. Data were analyzed in unpaired t tests with Holm-Sidak correction for multiple comparisons and significance at p < .05 using GraphPad Prism 6 software. Significant differences between the HIV-GFP+ and bystander groups are indicated in bold and by an asterisk.