Antiviral breadth of KR13 induced virolysis. Dose responses, shown by sigmoidal curve fits, were obtained using Origin Pro. 8 (explained in Methods section) for p24 release induced by KR13 ranging from 1 nM to 50 μM from several clades of HIV-1 pseudoviruses (a) and transmitted founder viruses (b). (c) Table of the IC50 values obtained from (a) and (b). Error bars represent the standard deviation of the mean, n = 3.