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Figure 5 | Retrovirology

Figure 5

From: Relative resistance of HIV-1 founder viruses to control by interferon-alpha

Figure 5

IFN-α and IFN-β resistance of viruses generated from IMCs corresponding to the deduced founder virus sequence from subjects in whom systemic HIV infection was established by a single virus. (A) IFNα (filled circles) and IFNβ (open triangles) IC50 values of founder virus IMCs from different subjects; and (B) IFNα (filled circles) and IFNβ (open triangles) Vres values of these founder virus IMCs. Each datapoint represents the mean (of results obtained in a minimum of 2 independent IFN inhibition assays) IC50 or Vres value calculated for a given virus. The horizontal lines show the group mean IC50 or Vres values, plus and minus one standard error.

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