From: Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage
This study
Human cells
Single-round/MT4
Multiple-round/MT4
2.4 ± 0.5 μM
0.17 ± 0.03 μM
Wang et al. study [40]
Mouse cells
LEDGF +/+ WT cells
LEDGF -/- KO cells
2.4 to 2.9 μM
0.16 to 0.20 μM