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Figure 2 | Retrovirology

Figure 2

From: Identification of late assembly domains of the human endogenous retrovirus-K(HML-2)

Figure 2

Schematic representation of a HERV-K(HML-2) provirus and the position of presumed L-domains within the Gag protein. Genomic structure of the provirus. The Gag protein encodes the matrix protein (MA), a spacer peptide (SP1), p15, capsid (CA), nucleocapsid (NC) and two small peptides (QP1 and QP2). A PTAP and two YPXnL motifs with presumed L-domain function are present in the p15 protein. A PPPQ sequence resembling a PPPY L-domain is present in QP2. The position of the first amino acid of each motif in the Gag protein of oriHERV-K113 is given.

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