Figure 4
From: Dual-acting stapled peptides target both HIV-1 entry and assembly
Inhibition of in vitro assembly by NYAD-36. Negatively stained EM images of mature-like particles resulting from in vitro assembly of CA proteins in the presence of (a) no peptide (Control), 0.25-, 0.5-, 1.0-, and 3-fold molar equivalent of NYAD-36. and 0.25-, 0.5-, 1.0-, 3.0- and 5-fold molar equivalent of NYAD-1. (b) Quantification of mature-like particles resulting from in vitro assembly of CA proteins in the presence of no peptide (Control), 0.25-, 0.5-, 1.0-, 3.0-fold molar equivalent of NYAD-36.