Figure 14
From: Dual-acting stapled peptides target both HIV-1 entry and assembly
Infectivity defects in the presence of stapled peptides are reversed by VSV-G pseudotyping. HIV-1 virions were pseudotyped with VSV-G as described in Figure 13. RT-normalized WT HIV-1 Env- and VSV-G-pseudotyped virions were used to infect TZM-bl cells in the presence of 50 μM of stapled peptides for 2 h. Two days after infection luciferase activity was xmeasured as in Figure 7. N = 6, ± SD.