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Figure 12 | Retrovirology

Figure 12

From: Dual-acting stapled peptides target both HIV-1 entry and assembly

Figure 12

V120Q/A327P mutant virions produced in the presence of stapled peptides were defective in single-cycle infectivity assay. 293T cells were transfected with WT and V120Q/A327P molecular clones, six hours posttransfection cells were treated with indicated concentrations of NYAD-36, -66, and -67 and virions were collected after 2 days as in Figure 7. RT-normalized virus stocks were used to infect TZM-bl cells and infectivity was measured as described in legend to Figure 7. N = 6, ± SD.

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