Skip to main content
Figure 3 | Retrovirology

Figure 3

From: Human Cytomegalovirus (HCMV) induces Human Endogenous Retrovirus (HERV) transcription

Figure 3

Effects of HCMV replication and IE on HERV-K(HML-2) transcription. A) RT activity in glioma initiating cells GliNS1 (A) 7 days post infection with 1 MOI HCMV or UV-inactivated HCMV and filtered HCMV (2 μm pore size); (n = 4); B) Effect of GCV on IEcDNA expression induced by HCMV strain VR 1814 (n = 3) 7 dpi; C) Effect of GCV on HML-2 transcription induced by HCMV strain VR 1814 (n = 3) 7 dpi; D) Effects of siRNA-IE72 and siRNA-IE86 on VR 1814 induced HML-2 transcription (n = 2). E) Effect of HCMV on LINE-1 expression in GliNS1 at 5 and 7 dpi (n = 3). F) Effect of HCMV on HML-2 expression in GliNS1 at 5 and 7 dpi (n = 3). Detailed information on the methods are described in the (Additional file 1). *p = <0.05 **p = <0.01.

Back to article page