TY - JOUR AU - Nisole, S. AU - Saib, A. PY - 2004 DA - 2004// TI - Early steps of retrovirus replicative cycle JO - Retrovirology VL - 1 UR - https://doi.org/10.1186/1742-4690-1-9 DO - 10.1186/1742-4690-1-9 ID - Nisole2004 ER - TY - JOUR AU - Bowerman, B. AU - Brown, P. O. AU - Bishop, J. M. AU - Varmus, H. E. PY - 1989 DA - 1989// TI - A nucleoprotein complex mediates the integration of retroviral DNA JO - Genes Dev VL - 3 UR - https://doi.org/10.1101/gad.3.4.469 DO - 10.1101/gad.3.4.469 ID - Bowerman1989 ER - TY - JOUR AU - Brown, P. O. AU - Bowerman, B. AU - Varmus, H. E. AU - Bishop, J. M. PY - 1987 DA - 1987// TI - Correct integration of retroviral DNA in vitro JO - Cell VL - 49 UR - https://doi.org/10.1016/0092-8674(87)90287-X DO - 10.1016/0092-8674(87)90287-X ID - Brown1987 ER - TY - JOUR AU - Fujiwara, T. AU - Mizuuchi, K. PY - 1988 DA - 1988// TI - Retroviral DNA integration: structure of an integration intermediate JO - Cell VL - 54 UR - https://doi.org/10.1016/0092-8674(88)90071-2 DO - 10.1016/0092-8674(88)90071-2 ID - Fujiwara1988 ER - TY - JOUR AU - Ellison, V. AU - Abrams, H. AU - Roe, T. AU - Lifson, J. AU - Brown, P. PY - 1990 DA - 1990// TI - Human immunodeficiency virus integration in a cell-free system JO - J Virol VL - 64 ID - Ellison1990 ER - TY - JOUR AU - Farnet, C. M. AU - Haseltine, W. A. PY - 1990 DA - 1990// TI - Integration of human immunodeficiency virus type 1 DNA in vitro JO - Proc Natl Acad Sci U S A VL - 87 UR - https://doi.org/10.1073/pnas.87.11.4164 DO - 10.1073/pnas.87.11.4164 ID - Farnet1990 ER - TY - JOUR AU - Hansen, M. S. AU - Bushman, F. D. PY - 1997 DA - 1997// TI - Human immunodeficiency virus type 2 preintegration complexes: activities in vitro and response to inhibitors JO - J Virol VL - 71 ID - Hansen1997 ER - TY - JOUR AU - Engelman, A. PY - 2009 DA - 2009// TI - Isolation and analysis of HIV-1 preintegration complexes JO - Methods Mol Biol VL - 485 UR - https://doi.org/10.1007/978-1-59745-170-3_10 DO - 10.1007/978-1-59745-170-3_10 ID - Engelman2009 ER - TY - JOUR AU - Bushman, F. D. AU - Fujiwara, T. AU - Craigie, R. PY - 1990 DA - 1990// TI - Retroviral DNA integration directed by HIV integration protein in vitro JO - Science VL - 249 UR - https://doi.org/10.1126/science.2171144 DO - 10.1126/science.2171144 ID - Bushman1990 ER - TY - JOUR AU - Craigie, R. AU - Fujiwara, T. AU - Bushman, F. PY - 1990 DA - 1990// TI - The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro JO - Cell VL - 62 UR - https://doi.org/10.1016/0092-8674(90)90126-Y DO - 10.1016/0092-8674(90)90126-Y ID - Craigie1990 ER - TY - JOUR AU - Engelman, A. AU - Mizuuchi, K. AU - Craigie, R. PY - 1991 DA - 1991// TI - HIV-1 DNA integration: mechanism of viral DNA cleavage and DNA strand transfer JO - Cell VL - 67 UR - https://doi.org/10.1016/0092-8674(91)90297-C DO - 10.1016/0092-8674(91)90297-C ID - Engelman1991 ER - TY - JOUR AU - Chen, H. AU - Wei, S. Q. AU - Engelman, A. PY - 1999 DA - 1999// TI - Multiple integrase functions are required to form the native structure of the human immunodeficiency virus type I intasome JO - J Biol Chem VL - 274 UR - https://doi.org/10.1074/jbc.274.24.17358 DO - 10.1074/jbc.274.24.17358 ID - Chen1999 ER - TY - JOUR AU - Wei, S. Q. AU - Mizuuchi, K. AU - Craigie, R. PY - 1997 DA - 1997// TI - A large nucleoprotein assembly at the ends of the viral DNA mediates retroviral DNA integration JO - EMBO J VL - 16 UR - https://doi.org/10.1093/emboj/16.24.7511 DO - 10.1093/emboj/16.24.7511 ID - Wei1997 ER - TY - JOUR AU - Wei, S. Q. AU - Mizuuchi, K. AU - Craigie, R. PY - 1998 DA - 1998// TI - Footprints on the viral DNA ends in moloney murine leukemia virus preintegration complexes reflect a specific association with integrase JO - Proc Natl Acad Sci U S A VL - 95 UR - https://doi.org/10.1073/pnas.95.18.10535 DO - 10.1073/pnas.95.18.10535 ID - Wei1998 ER - TY - JOUR AU - Brown, P. O. AU - Bowerman, B. AU - Varmus, H. E. AU - Bishop, J. M. PY - 1989 DA - 1989// TI - Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein JO - Proc Natl Acad Sci U S A VL - 86 UR - https://doi.org/10.1073/pnas.86.8.2525 DO - 10.1073/pnas.86.8.2525 ID - Brown1989 ER - TY - JOUR AU - Pauza, C. D. PY - 1990 DA - 1990// TI - Two bases are deleted from the termini of HIV-1 linear DNA during integrative recombination JO - Virology VL - 179 UR - https://doi.org/10.1016/0042-6822(90)90161-J DO - 10.1016/0042-6822(90)90161-J ID - Pauza1990 ER - TY - JOUR AU - Yoder, K. E. AU - Bushman, F. D. PY - 2000 DA - 2000// TI - Repair of gaps in retroviral DNA integration intermediates JO - J Virol VL - 74 UR - https://doi.org/10.1128/JVI.74.23.11191-11200.2000 DO - 10.1128/JVI.74.23.11191-11200.2000 ID - Yoder2000 ER - TY - JOUR AU - Vincent, K. A. AU - York-Higgins, D. AU - Quiroga, M. AU - Brown, P. O. PY - 1990 DA - 1990// TI - Host sequences flanking the HIV provirus JO - Nucleic Acids Res VL - 18 UR - https://doi.org/10.1093/nar/18.20.6045 DO - 10.1093/nar/18.20.6045 ID - Vincent1990 ER - TY - JOUR AU - Bukrinsky, M. I. AU - Sharova, N. AU - McDonald, T. L. AU - Pushkarskaya, T. AU - Tarpley, W. G. AU - Stevenson, M. PY - 1993 DA - 1993// TI - Association of integrase, matrix, and reverse transcriptase antigens of human immunodeficiency virus type 1 with viral nucleic acids following acute infection JO - Proc Natl Acad Sci U S A VL - 90 UR - https://doi.org/10.1073/pnas.90.13.6125 DO - 10.1073/pnas.90.13.6125 ID - Bukrinsky1993 ER - TY - JOUR AU - Farnet, C. M. AU - Bushman, F. D. PY - 1997 DA - 1997// TI - HIV-1 cDNA integration: requirement of HMG I(Y) protein for function of preintegration complexes in vitro JO - Cell VL - 88 UR - https://doi.org/10.1016/S0092-8674(00)81888-7 DO - 10.1016/S0092-8674(00)81888-7 ID - Farnet1997 ER - TY - JOUR AU - Farnet, C. M. AU - Haseltine, W. A. PY - 1991 DA - 1991// TI - Determination of viral proteins present in the human immunodeficiency virus type 1 preintegration complex JO - J Virol VL - 65 ID - Farnet1991 ER - TY - JOUR AU - Gallay, P. AU - Swingler, S. AU - Song, J. AU - Bushman, F. AU - Trono, D. PY - 1995 DA - 1995// TI - HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase JO - Cell VL - 83 UR - https://doi.org/10.1016/0092-8674(95)90097-7 DO - 10.1016/0092-8674(95)90097-7 ID - Gallay1995 ER - TY - JOUR AU - Iordanskiy, S. AU - Berro, R. AU - Altieri, M. AU - Kashanchi, F. AU - Bukrinsky, M. PY - 2006 DA - 2006// TI - Intracytoplasmic maturation of the human immunodeficiency virus type 1 reverse transcription complexes determines their capacity to integrate into chromatin JO - Retrovirology VL - 3 UR - https://doi.org/10.1186/1742-4690-3-4 DO - 10.1186/1742-4690-3-4 ID - Iordanskiy2006 ER - TY - JOUR AU - Karageorgos, L. AU - Li, P. AU - Burrell, C. PY - 1993 DA - 1993// TI - Characterization of HIV replication complexes early after cell-to-cell infection JO - AIDS Res Hum Retroviruses VL - 9 UR - https://doi.org/10.1089/aid.1993.9.817 DO - 10.1089/aid.1993.9.817 ID - Karageorgos1993 ER - TY - JOUR AU - Miller, M. D. AU - Farnet, C. M. AU - Bushman, F. D. PY - 1997 DA - 1997// TI - Human immunodeficiency virus type 1 preintegration complexes: studies of organization and composition JO - J Virol VL - 71 ID - Miller1997 ER - TY - JOUR AU - Li, L. AU - Yoder, K. AU - Hansen, M. S. AU - Olvera, J. AU - Miller, M. D. AU - Bushman, F. D. PY - 2000 DA - 2000// TI - Retroviral cDNA integration: stimulation by HMG I family proteins JO - J Virol VL - 74 UR - https://doi.org/10.1128/JVI.74.23.10965-10974.2000 DO - 10.1128/JVI.74.23.10965-10974.2000 ID - Li2000 ER - TY - JOUR AU - Li, L. AU - Olvera, J. M. AU - Yoder, K. E. AU - Mitchell, R. S. AU - Butler, S. L. AU - Lieber, M. AU - Martin, S. L. AU - Bushman, F. D. PY - 2001 DA - 2001// TI - Role of the non-homologous DNA end joining pathway in the early steps of retroviral infection JO - EMBO J VL - 20 UR - https://doi.org/10.1093/emboj/20.12.3272 DO - 10.1093/emboj/20.12.3272 ID - Li2001 ER - TY - JOUR AU - Lin, C. W. AU - Engelman, A. PY - 2003 DA - 2003// TI - The barrier-to-autointegration factor is a component of functional human immunodeficiency virus type 1 preintegration complexes JO - J Virol VL - 77 UR - https://doi.org/10.1128/JVI.77.8.5030-5036.2003 DO - 10.1128/JVI.77.8.5030-5036.2003 ID - Lin2003 ER - TY - JOUR AU - Llano, M. AU - Vanegas, M. AU - Fregoso, O. AU - Saenz, D. AU - Chung, S. AU - Peretz, M. AU - Poeschla, E. M. PY - 2004 DA - 2004// TI - LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes JO - J Virol VL - 78 UR - https://doi.org/10.1128/JVI.78.17.9524-9537.2004 DO - 10.1128/JVI.78.17.9524-9537.2004 ID - Llano2004 ER - TY - JOUR AU - Suzuki, Y. AU - Craigie, R. PY - 2007 DA - 2007// TI - The road to chromatin - nuclear entry of retroviruses JO - Nat Rev Microbiol VL - 5 UR - https://doi.org/10.1038/nrmicro1579 DO - 10.1038/nrmicro1579 ID - Suzuki2007 ER - TY - JOUR AU - Arhel, N. J. AU - Souquere-Besse, S. AU - Munier, S. AU - Souque, P. AU - Guadagnini, S. AU - Rutherford, S. AU - Prevost, M. C. AU - Allen, T. D. AU - Charneau, P. PY - 2007 DA - 2007// TI - HIV-1 DNA Flap formation promotes uncoating of the pre-integration complex at the nuclear pore JO - EMBO J VL - 26 UR - https://doi.org/10.1038/sj.emboj.7601740 DO - 10.1038/sj.emboj.7601740 ID - Arhel2007 ER - TY - JOUR AU - Zennou, V. AU - Petit, C. AU - Guetard, D. AU - Nerhbass, U. AU - Montagnier, L. AU - Charneau, P. PY - 2000 DA - 2000// TI - HIV-1 genome nuclear import is mediated by a central DNA flap JO - Cell VL - 101 UR - https://doi.org/10.1016/S0092-8674(00)80828-4 DO - 10.1016/S0092-8674(00)80828-4 ID - Zennou2000 ER - TY - JOUR AU - Yamashita, M. AU - Emerman, M. PY - 2005 DA - 2005// TI - The cell cycle independence of HIV infections is not determined by known karyophilic viral elements JO - PLoS Pathog VL - 1 UR - https://doi.org/10.1371/journal.ppat.0010018 DO - 10.1371/journal.ppat.0010018 ID - Yamashita2005 ER - TY - JOUR AU - Yamashita, M. AU - Perez, O. AU - Hope, T. J. AU - Emerman, M. PY - 2007 DA - 2007// TI - Evidence for direct involvement of the capsid protein in HIV infection of nondividing cells JO - PLoS Pathog VL - 3 UR - https://doi.org/10.1371/journal.ppat.0030156 DO - 10.1371/journal.ppat.0030156 ID - Yamashita2007 ER - TY - JOUR AU - Brass, A. L. AU - Dykxhoorn, D. M. AU - Benita, Y. AU - Yan, N. AU - Engelman, A. AU - Xavier, R. J. AU - Lieberman, J. AU - Elledge, S. J. PY - 2008 DA - 2008// TI - Identification of host proteins required for HIV infection through a functional genomic screen JO - Science VL - 319 UR - https://doi.org/10.1126/science.1152725 DO - 10.1126/science.1152725 ID - Brass2008 ER - TY - JOUR AU - Christ, F. AU - Thys, W. AU - De Rijck, J. AU - Gijsbers, R. AU - Albanese, A. AU - Arosio, D. AU - Emiliani, S. AU - Rain, J. C. AU - Benarous, R. AU - Cereseto, A. AU - Debyser, Z. PY - 2008 DA - 2008// TI - Transportin-SR2 imports HIV into the nucleus JO - Curr Biol VL - 18 UR - https://doi.org/10.1016/j.cub.2008.07.079 DO - 10.1016/j.cub.2008.07.079 ID - Christ2008 ER - TY - JOUR AU - Konig, R. AU - Zhou, Y. AU - Elleder, D. AU - Diamond, T. L. AU - Bonamy, G. M. AU - Irelan, J. T. AU - Chiang, C. Y. AU - Tu, B. P. AU - De Jesus, P. D. AU - Lilley, C. E. PY - 2008 DA - 2008// TI - Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication JO - Cell VL - 135 UR - https://doi.org/10.1016/j.cell.2008.07.032 DO - 10.1016/j.cell.2008.07.032 ID - Konig2008 ER - TY - JOUR AU - De Iaco, A. AU - Luban, J. PY - 2011 DA - 2011// TI - Inhibition of HIV-1 infection by TNPO3 depletion is determined by capsid and detectable after viral cDNA enters the nucleus JO - Retrovirology VL - 8 UR - https://doi.org/10.1186/1742-4690-8-98 DO - 10.1186/1742-4690-8-98 ID - De Iaco2011 ER - TY - JOUR AU - Schaller, T. AU - Ocwieja, K. E. AU - Rasaiyaah, J. AU - Price, A. J. AU - Brady, T. L. AU - Roth, S. L. AU - Hue, S. AU - Fletcher, A. J. AU - Lee, K. AU - Kewalramani, V. N. PY - 2011 DA - 2011// TI - HIV-1 capsid-cyclophilin interactions determine nuclear import pathway. Integration targeting and replication efficiency JO - PLoS Pathog VL - 7 UR - https://doi.org/10.1371/journal.ppat.1002439 DO - 10.1371/journal.ppat.1002439 ID - Schaller2011 ER - TY - JOUR AU - Zhou, L. AU - Sokolskaja, E. AU - Jolly, C. AU - James, W. AU - Cowley, S. A. AU - Fassati, A. PY - 2011 DA - 2011// TI - Transportin 3 promotes a nuclear maturation step required for efficient HIV-1 integration JO - PLoS Pathog VL - 7 UR - https://doi.org/10.1371/journal.ppat.1002194 DO - 10.1371/journal.ppat.1002194 ID - Zhou2011 ER - TY - JOUR AU - Kataoka, N. AU - Bachorik, J. L. AU - Dreyfuss, G. PY - 1999 DA - 1999// TI - Transportin-SR, a nuclear import receptor for SR proteins JO - J Cell Biol VL - 145 UR - https://doi.org/10.1083/jcb.145.6.1145 DO - 10.1083/jcb.145.6.1145 ID - Kataoka1999 ER - TY - JOUR AU - Rain, J. C. AU - Cribier, A. AU - Gerard, A. AU - Emiliani, S. AU - Benarous, R. PY - 2009 DA - 2009// TI - Yeast two-hybrid detection of integrase-host factor interactions JO - Methods VL - 47 UR - https://doi.org/10.1016/j.ymeth.2009.02.002 DO - 10.1016/j.ymeth.2009.02.002 ID - Rain2009 ER - TY - JOUR AU - Cribier, A. AU - Segeral, E. AU - Delelis, O. AU - Parissi, V. AU - Simon, A. AU - Ruff, M. AU - Benarous, R. AU - Emiliani, S. PY - 2011 DA - 2011// TI - Mutations affecting interaction of integrase with TNPO3 do not prevent HIV-1 cDNA nuclear import JO - Retrovirology VL - 8 UR - https://doi.org/10.1186/1742-4690-8-104 DO - 10.1186/1742-4690-8-104 ID - Cribier2011 ER - TY - JOUR AU - Krishnan, L. AU - Matreyek, K. A. AU - Oztop, I. AU - Lee, K. AU - Tipper, C. H. AU - Li, X. AU - Dar, M. J. AU - Kewalramani, V. N. AU - Engelman, A. PY - 2010 DA - 2010// TI - The requirement for cellular transportin 3 (TNPO3 or TRN-SR2) during infection maps to human immunodeficiency virus type 1 capsid and not integrase JO - J Virol VL - 84 UR - https://doi.org/10.1128/JVI.01899-09 DO - 10.1128/JVI.01899-09 ID - Krishnan2010 ER - TY - JOUR AU - Thys, W. AU - De Houwer, S. AU - Demeulemeester, J. AU - Taltynov, O. AU - Vancraenenbroeck, R. AU - Gerard, M. AU - De Rijck, J. AU - Gijsbers, R. AU - Christ, F. AU - Debyser, Z. PY - 2011 DA - 2011// TI - Interplay between HIV entry and transportin-SR2 dependency JO - Retrovirology VL - 8 UR - https://doi.org/10.1186/1742-4690-8-7 DO - 10.1186/1742-4690-8-7 ID - Thys2011 ER - TY - JOUR AU - Cherepanov, P. AU - Maertens, G. N. AU - Hare, S. PY - 2011 DA - 2011// TI - Structural insights into the retroviral DNA integration apparatus JO - Curr Opin Struct Biol VL - 21 UR - https://doi.org/10.1016/j.sbi.2010.12.005 DO - 10.1016/j.sbi.2010.12.005 ID - Cherepanov2011 ER - TY - JOUR AU - Li, X. AU - Krishnan, L. AU - Cherepanov, P. AU - Engelman, A. PY - 2011 DA - 2011// TI - Structural biology of retroviral DNA integration JO - Virology VL - 411 UR - https://doi.org/10.1016/j.virol.2010.12.008 DO - 10.1016/j.virol.2010.12.008 ID - Li2011 ER - TY - JOUR AU - Ciuffi, A. AU - Llano, M. AU - Poeschla, E. AU - Hoffmann, C. AU - Leipzig, J. AU - Shinn, P. AU - Ecker, J. R. AU - Bushman, F. PY - 2005 DA - 2005// TI - A role for LEDGF/p75 in targeting HIV DNA integration JO - Nat Med VL - 11 UR - https://doi.org/10.1038/nm1329 DO - 10.1038/nm1329 ID - Ciuffi2005 ER - TY - JOUR AU - Marshall, H. M. AU - Ronen, K. AU - Berry, C. AU - Llano, M. AU - Sutherland, H. AU - Saenz, D. AU - Bickmore, W. AU - Poeschla, E. AU - Bushman, F. D. PY - 2007 DA - 2007// TI - Role of PSIP1/LEDGF/p75 in lentiviral infectivity and integration targeting JO - PLoS One VL - 2 UR - https://doi.org/10.1371/journal.pone.0001340 DO - 10.1371/journal.pone.0001340 ID - Marshall2007 ER - TY - JOUR AU - Shun, M. C. AU - Raghavendra, N. K. AU - Vandegraaff, N. AU - Daigle, J. E. AU - Hughes, S. AU - Kellam, P. AU - Cherepanov, P. AU - Engelman, A. PY - 2007 DA - 2007// TI - LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration JO - Genes Dev VL - 21 UR - https://doi.org/10.1101/gad.1565107 DO - 10.1101/gad.1565107 ID - Shun2007 ER - TY - JOUR AU - Cherepanov, P. AU - Maertens, G. AU - Proost, P. AU - Devreese, B. AU - Van Beeumen, J. AU - Engelborghs, Y. AU - De Clercq, E. AU - Debyser, Z. PY - 2003 DA - 2003// TI - HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells JO - J Biol Chem VL - 278 UR - https://doi.org/10.1074/jbc.M209278200 DO - 10.1074/jbc.M209278200 ID - Cherepanov2003 ER - TY - JOUR AU - Emiliani, S. AU - Mousnier, A. AU - Busschots, K. AU - Maroun, M. AU - Van Maele, B. AU - Tempe, D. AU - Vandekerckhove, L. AU - Moisant, F. AU - Ben-Slama, L. AU - Witvrouw, M. PY - 2005 DA - 2005// TI - Integrase mutants defective for interaction with LEDGF/p75 are impaired in chromosome tethering and HIV-1 replication JO - J Biol Chem VL - 280 UR - https://doi.org/10.1074/jbc.M501378200 DO - 10.1074/jbc.M501378200 ID - Emiliani2005 ER - TY - JOUR AU - Turlure, F. AU - Devroe, E. AU - Silver, P. A. AU - Engelman, A. PY - 2004 DA - 2004// TI - Human cell proteins and human immunodeficiency virus DNA integration JO - Front Biosci VL - 9 UR - https://doi.org/10.2741/1472 DO - 10.2741/1472 ID - Turlure2004 ER - TY - JOUR AU - Ge, H. AU - Roeder, R. G. PY - 1994 DA - 1994// TI - Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes JO - Cell VL - 78 UR - https://doi.org/10.1016/0092-8674(94)90428-6 DO - 10.1016/0092-8674(94)90428-6 ID - Ge1994 ER - TY - JOUR AU - Ge, H. AU - Si, Y. AU - Roeder, R. G. PY - 1998 DA - 1998// TI - Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation JO - EMBO J VL - 17 UR - https://doi.org/10.1093/emboj/17.22.6723 DO - 10.1093/emboj/17.22.6723 ID - Ge1998 ER - TY - JOUR AU - Yokoyama, A. AU - Cleary, M. L. PY - 2008 DA - 2008// TI - Menin critically links MLL proteins with LEDGF on cancer-associated target genes JO - Cancer Cell VL - 14 UR - https://doi.org/10.1016/j.ccr.2008.05.003 DO - 10.1016/j.ccr.2008.05.003 ID - Yokoyama2008 ER - TY - JOUR AU - Engelman, A. AU - Cherepanov, P. PY - 2008 DA - 2008// TI - The lentiviral integrase binding protein LEDGF/p75 and HIV-1 replication JO - PLoS Pathog VL - 4 UR - https://doi.org/10.1371/journal.ppat.1000046 DO - 10.1371/journal.ppat.1000046 ID - Engelman2008 ER - TY - JOUR AU - Poeschla, E. M. PY - 2008 DA - 2008// TI - Integrase, LEDGF/p75 and HIV replication JO - Cell Mol Life Sci VL - 65 UR - https://doi.org/10.1007/s00018-008-7540-5 DO - 10.1007/s00018-008-7540-5 ID - Poeschla2008 ER - TY - JOUR AU - Busschots, K. AU - Voet, A. AU - De Maeyer, M. AU - Rain, J. C. AU - Emiliani, S. AU - Benarous, R. AU - Desender, L. AU - Debyser, Z. AU - Christ, F. PY - 2007 DA - 2007// TI - Identification of the LEDGF/p75 binding site in HIV-1 integrase JO - J Mol Biol VL - 365 UR - https://doi.org/10.1016/j.jmb.2006.10.094 DO - 10.1016/j.jmb.2006.10.094 ID - Busschots2007 ER - TY - JOUR AU - Cherepanov, P. AU - Sun, Z. Y. AU - Rahman, S. AU - Maertens, G. AU - Wagner, G. AU - Engelman, A. PY - 2005 DA - 2005// TI - Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75 JO - Nat Struct Mol Biol VL - 12 UR - https://doi.org/10.1038/nsmb937 DO - 10.1038/nsmb937 ID - Cherepanov2005 ER - TY - JOUR AU - Rahman, S. AU - Lu, R. AU - Vandegraaff, N. AU - Cherepanov, P. AU - Engelman, A. PY - 2007 DA - 2007// TI - Structure-based mutagenesis of the integrase-LEDGF/p75 interface uncouples a strict correlation between in vitro protein binding and HIV-1 fitness JO - Virology VL - 357 UR - https://doi.org/10.1016/j.virol.2006.08.011 DO - 10.1016/j.virol.2006.08.011 ID - Rahman2007 ER - TY - JOUR AU - De Rijck, J. AU - Vandekerckhove, L. AU - Gijsbers, R. AU - Hombrouck, A. AU - Hendrix, J. AU - Vercammen, J. AU - Engelborghs, Y. AU - Christ, F. AU - Debyser, Z. PY - 2006 DA - 2006// TI - Overexpression of the lens epithelium-derived growth factor/p75 integrase binding domain inhibits human immunodeficiency virus replication JO - J Virol VL - 80 UR - https://doi.org/10.1128/JVI.00801-06 DO - 10.1128/JVI.00801-06 ID - De Rijck2006 ER - TY - JOUR AU - Llano, M. AU - Vanegas, M. AU - Hutchins, N. AU - Thompson, D. AU - Delgado, S. AU - Poeschla, E. M. PY - 2006 DA - 2006// TI - Identification and characterization of the chromatin-binding domains of the HIV-1 integrase interactor LEDGF/p75 JO - J Mol Biol VL - 360 UR - https://doi.org/10.1016/j.jmb.2006.04.073 DO - 10.1016/j.jmb.2006.04.073 ID - Llano2006 ER - TY - JOUR AU - Vandekerckhove, L. AU - Christ, F. AU - Van Maele, B. AU - De Rijck, J. AU - Gijsbers, R. AU - Van den Haute, C. AU - Witvrouw, M. AU - Debyser, Z. PY - 2006 DA - 2006// TI - Transient and stable knockdown of the integrase cofactor LEDGF/p75 reveals its role in the replication cycle of human immunodeficiency virus JO - J Virol VL - 80 UR - https://doi.org/10.1128/JVI.80.4.1886-1896.2006 DO - 10.1128/JVI.80.4.1886-1896.2006 ID - Vandekerckhove2006 ER - TY - JOUR AU - Zielske, S. P. AU - Stevenson, M. PY - 2006 DA - 2006// TI - Modest but reproducible inhibition of human immunodeficiency virus type 1 infection in macrophages following LEDGFp75 silencing JO - J Virol VL - 80 UR - https://doi.org/10.1128/JVI.02470-05 DO - 10.1128/JVI.02470-05 ID - Zielske2006 ER - TY - JOUR AU - Cherepanov, P. AU - Ambrosio, A. L. AU - Rahman, S. AU - Ellenberger, T. AU - Engelman, A. PY - 2005 DA - 2005// TI - Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75 JO - Proc Natl Acad Sci U S A VL - 102 UR - https://doi.org/10.1073/pnas.0506924102 DO - 10.1073/pnas.0506924102 ID - Cherepanov2005 ER - TY - JOUR AU - Hare, S. AU - Shun, M. C. AU - Gupta, S. S. AU - Valkov, E. AU - Engelman, A. AU - Cherepanov, P. PY - 2009 DA - 2009// TI - A novel co-crystal structure affords the design of gain-of-function lentiviral integrase mutants in the presence of modified PSIP1/LEDGF/p75 JO - PLoS Pathog VL - 5 UR - https://doi.org/10.1371/journal.ppat.1000259 DO - 10.1371/journal.ppat.1000259 ID - Hare2009 ER - TY - JOUR AU - Petit, C. AU - Schwartz, O. AU - Mammano, F. PY - 1999 DA - 1999// TI - Oligomerization within virions and subcellular localization of human immunodeficiency virus type 1 integrase JO - J Virol VL - 73 ID - Petit1999 ER - TY - JOUR AU - Gabuzda, D. H. AU - Lawrence, K. AU - Langhoff, E. AU - Terwilliger, E. AU - Dorfman, T. AU - Haseltine, W. A. AU - Sodroski, J. PY - 1992 DA - 1992// TI - Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes JO - J Virol VL - 66 ID - Gabuzda1992 ER - TY - JOUR AU - Mulder, L. C. AU - Muesing, M. A. PY - 2000 DA - 2000// TI - Degradation of HIV-1 integrase by the N-end rule pathway JO - J Biol Chem VL - 275 UR - https://doi.org/10.1074/jbc.M004670200 DO - 10.1074/jbc.M004670200 ID - Mulder2000 ER - TY - JOUR AU - Mousnier, A. AU - Kubat, N. AU - Massias-Simon, A. AU - Segeral, E. AU - Rain, J. C. AU - Benarous, R. AU - Emiliani, S. AU - Dargemont, C. PY - 2007 DA - 2007// TI - von Hippel Lindau binding protein 1-mediated degradation of integrase affects HIV-1 gene expression at a postintegration step JO - Proc Natl Acad Sci U S A VL - 104 UR - https://doi.org/10.1073/pnas.0705162104 DO - 10.1073/pnas.0705162104 ID - Mousnier2007 ER - TY - JOUR AU - Llano, M. AU - Saenz, D. T. AU - Meehan, A. AU - Wongthida, P. AU - Peretz, M. AU - Walker, W. H. AU - Teo, W. AU - Poeschla, E. M. PY - 2006 DA - 2006// TI - An essential role for LEDGF/p75 in HIV integration JO - Science VL - 314 UR - https://doi.org/10.1126/science.1132319 DO - 10.1126/science.1132319 ID - Llano2006 ER - TY - JOUR AU - Li, X. AU - Koh, Y. AU - Engelman, A. PY - 2012 DA - 2012// TI - Correlation of recombinant integrase activity and functional preintegration complex formation during acute infection by replication-defective integrase mutant human immunodeficiency virus JO - J Virol VL - 86 UR - https://doi.org/10.1128/JVI.06386-11 DO - 10.1128/JVI.06386-11 ID - Li2012 ER - TY - JOUR AU - Devroe, E. AU - Engelman, A. AU - Silver, P. A. PY - 2003 DA - 2003// TI - Intracellular transport of human immunodeficiency virus type 1 integrase JO - J Cell Sci VL - 116 UR - https://doi.org/10.1242/jcs.00747 DO - 10.1242/jcs.00747 ID - Devroe2003 ER - TY - JOUR AU - Llano, M. AU - Delgado, S. AU - Vanegas, M. AU - Poeschla, E. M. PY - 2004 DA - 2004// TI - Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase JO - J Biol Chem VL - 279 UR - https://doi.org/10.1074/jbc.M408508200 DO - 10.1074/jbc.M408508200 ID - Llano2004 ER - TY - JOUR AU - Tasaki, T. AU - Mulder, L. C. AU - Iwamatsu, A. AU - Lee, M. J. AU - Davydov, I. V. AU - Varshavsky, A. AU - Muesing, M. AU - Kwon, Y. T. PY - 2005 DA - 2005// TI - A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons JO - Mol Cell Biol VL - 25 UR - https://doi.org/10.1128/MCB.25.16.7120-7136.2005 DO - 10.1128/MCB.25.16.7120-7136.2005 ID - Tasaki2005 ER - TY - JOUR AU - Gallay, P. AU - Swingler, S. AU - Aiken, C. AU - Trono, D. PY - 1995 DA - 1995// TI - HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator JO - Cell VL - 80 UR - https://doi.org/10.1016/0092-8674(95)90488-3 DO - 10.1016/0092-8674(95)90488-3 ID - Gallay1995 ER - TY - JOUR AU - Brussel, A. AU - Sonigo, P. PY - 2003 DA - 2003// TI - Analysis of early human immunodeficiency virus type 1 DNA synthesis by use of a new sensitive assay for quantifying integrated provirus JO - J Virol VL - 77 UR - https://doi.org/10.1128/JVI.77.18.10119-10124.2003 DO - 10.1128/JVI.77.18.10119-10124.2003 ID - Brussel2003 ER - TY - JOUR AU - Thomas, J. A. AU - Ott, D. E. AU - Gorelick, R. J. PY - 2007 DA - 2007// TI - Efficiency of human immunodeficiency virus type 1 postentry infection processes: evidence against disproportionate numbers of defective virions JO - J Virol VL - 81 UR - https://doi.org/10.1128/JVI.02357-06 DO - 10.1128/JVI.02357-06 ID - Thomas2007 ER - TY - JOUR AU - Yan, N. AU - Regalado-Magdos, A. D. AU - Stiggelbout, B. AU - Lee-Kirsch, M. A. AU - Lieberman, J. PY - 2010 DA - 2010// TI - The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1 JO - Nat Immunol VL - 11 UR - https://doi.org/10.1038/ni.1941 DO - 10.1038/ni.1941 ID - Yan2010 ER - TY - CHAP AU - Swanstrom, R. AU - Wills, J. W. ED - Coffin, J. M. PY - 1997 DA - 1997// TI - Synthesis, assembly, and processing of viral proteins BT - Retroviruses PB - Cold Spring Harbor Laboratory Press CY - Plainview, New York ID - Swanstrom1997 ER - TY - JOUR AU - Hare, S. AU - Gupta, S. S. AU - Valkov, E. AU - Engelman, A. AU - Cherepanov, P. PY - 2010 DA - 2010// TI - Retroviral intasome assembly and inhibition of DNA strand transfer JO - Nature VL - 464 UR - https://doi.org/10.1038/nature08784 DO - 10.1038/nature08784 ID - Hare2010 ER - TY - JOUR AU - Krishnan, L. AU - Li, X. AU - Naraharisetty, H. L. AU - Hare, S. AU - Cherepanov, P. AU - Engelman, A. PY - 2010 DA - 2010// TI - Structure-based modeling of the functional HIV-1 intasome and its inhibition JO - Proc Natl Acad Sci U S A VL - 107 UR - https://doi.org/10.1073/pnas.1002346107 DO - 10.1073/pnas.1002346107 ID - Krishnan2010 ER - TY - JOUR AU - Maroun, M. AU - Delelis, O. AU - Coadou, G. AU - Bader, T. AU - Segeral, E. AU - Mbemba, G. AU - Petit, C. AU - Sonigo, P. AU - Rain, J. C. AU - Mouscadet, J. F. PY - 2006 DA - 2006// TI - Inhibition of early steps of HIV-1 replication by SNF5/Ini1 JO - J Biol Chem VL - 281 UR - https://doi.org/10.1074/jbc.M604849200 DO - 10.1074/jbc.M604849200 ID - Maroun2006 ER - TY - JOUR AU - Naldini, L. AU - Blomer, U. AU - Gage, F. H. AU - Trono, D. AU - Verma, I. M. PY - 1996 DA - 1996// TI - Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector JO - Proc Natl Acad Sci U S A VL - 93 UR - https://doi.org/10.1073/pnas.93.21.11382 DO - 10.1073/pnas.93.21.11382 ID - Naldini1996 ER -