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Table 1 Relative cloning frequencies of HERV-K(HML-2) loci transcribed in ESC, iPSC and ECC lines

From: Human endogenous retrovirus K (HML-2) RNA and protein expression is a marker for human embryonic and induced pluripotent stem cells

   

ESC

ESC

ESC

iPSC

iPSC

iPSC

iPSC

iPSC

iPSC

ECC

ECC

ECC

Alias

Type

ORF

BG01

H1

H9

MRC

MRC

MSC

MSC

hFib2

hFib2

GH

NCCIT

2102

      

iPS7

iPS20

iPS1

iPS3

iPS4

iPS5

  

Ep

K101(22q11.21)

1

g/n

64

60

57

69

61

56

88

62

39

75

16

29

ERVK-24

              

K10(5q33.3)

1

g/prt/n

-

26

7,3

8

23

5,5

6

-

22

8,5

21

-

ERVK-10

              

K109(6q14.1)

2

g/prt/e/r

-

7

7,3

-

8

-

-

-

-

-

-

42

ERVK-9

              

K106(3q13.2)

1

g/n

-

-

-

-

-

5,5

-

8

11

-

5

-

ERVK-3

              

K37(11q23.3)

1

g/prt/n

36

-

14

15

8

22

-

15

16

-

-

-

ERVK-20

              

HKc10-B(10q24.2)

2

g/r

-

7

7

-

-

11

-

-

6

-

-

-

ERVK-17

              

KI(3q21.2)

2

r

-

-

-

8

-

-

6

-

6

-

-

-

ERVK-4

              

K115(8p23.1)

2

pol/e/r

-

-

-

-

-

-

-

15

-

-

-

-

ERVK-8

              

K41(12q14.1)

2

g/prt/e/r

-

-

7,3

-

-

-

-

-

-

-

-

-

ERVK-21

              

K108(7p22.1)

2

g/prt/e/r

-

-

-

-

-

-

-

-

-

16,5

11

29

ERVK-6

              

K102(1q22)

1

n

-

-

-

-

-

-

-

-

-

-

47

-

ERVK-7

              
  1. Proviruses are designated by name and chromosomal locus, by type and putative open reading frames (ORF). For each cell line the relative cloning frequencies of the respective HERV-K(HML-2) loci are given as % (number of sequences assigned to the locus divided by the total number of sequences generated from the cDNA sample). 14 clones were generated and analyzed for BG01, 2102Ep, H9; 15 for H1; 13 for MRCiPS7, MRCiPS20, hFib2iPS4; 17 for MSCiPS3; 18 for hFib2iPS5; 19 for MSCiPS1 and NCCIT, 24 for GH. Open reading frames for Gag (g), Protease (prt) Envelope (e), Rec (r) NP9 (n).