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Figure 5 | Retrovirology

Figure 5

From: Novel preclinical models of topical PrEP pharmacodynamics provide rationale for combination of drugs with complementary properties

Figure 5

PK/PD correlations. Inhibition of HIV-1Ba-L infection in co-cultures of proximal (A) and distal (B) biopsies was correlated with IQP-0528 levels in biopsy tissue. Crosses represent biopsies obtained from animals exposed to placebo IVRs. Open and closed squares represent biopsies collected from animals exposed to IQP-0528 IVRs at 7 and 14 days post-IVR insertion, respectively. The Spearman correlation coefficient (ρ) is indicated.

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Retrovirology

ISSN: 1742-4690

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