Figure 6
Summary of ESCRT proteins and interactions that contribute to EIAV budding. EIAV Gag, cellular ESCRT proteins, and their protein-protein interactions (solid arrows) shown here to be involved in EIAV budding are depicted schematically. ALIX interactions with ubiquitin (Ub) and NCGag interactions previously shown to contribute to virus release are depicted with dotted arrows. Specific residues whose mutation inhibit the different interactions are given at right, together with their location within the relevant protein.