Figure 4

The Fv1 specific inhibition of MLV infection. There are two major alleles of the gene Fv1 among inbred mice, Fv1ⁿ and Fv1^b. Mice that carry the Fv1ⁿ allele are protected from B-tropic MLV infection (MLV B), whereas those carrying the Fv1ⁿ allele cannot be infected by N-tropic strains (MLV N). See text for detailed discussion. Abbreviations: MLV, murine leukemia virus.