Figure 6

Enzymatic assays of caspases in JPX-9 cell treated with Zn or Cd. Spectrophotometric assays of caspase activities are as described in Methods. Caspase 3 (A), caspase 8 (B), and caspase 9 activities were measured in cells 24 hours after treatment. Caspase 9 activity was especially enhanced in JPX-9 cells treated with Zn (C).