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Figure 5 | Retrovirology

Figure 5

From: Two discrete events, human T-cell leukemia virus type I Tax oncoprotein expression and a separate stress stimulus, are required for induction of apoptosis in T-cells

Figure 5

Western blotting analyses of caspase-3, -8, -9, Bcl-2, survivin and XIAP in Jurkat and JPX-9 cells after Zn or Cd treatment. A) Enhanced processing of pro-caspase 9 in JPX-9 cells after Zn treatment. Expression of pro-caspase-3, -8, and -9 in Jurkat and JPX-9 cells were checked by Western blotting. Jurkat and JPX-9 cells were treated with ZnCl2 or CdCl2 for 24 hours, and the indicated proteins were detected using specific anti-sera. Ratio is the band intensity in treated sample versus untreated control. B) Expression of Bcl-2, survivin and XIAP in Jurkat and JPX-9 cells. Jurkat and JPX-9 cells were treated with ZnCl2 or CdCl2 for 24 hours. Note that XIAP expression in ZnCl2 treated JPX-9 cells was reduced while its expression in CdCl2-treated JPX-9 cells was maintained.

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Retrovirology

ISSN: 1742-4690

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