Figure 4

Zn activated phosphorylated SAPK/JNK in Jurkat and JPX-9 cells. Western blotting detected phosphorylated c-Jun within 6 hours after Zn treatment (A), but was not seen after Cd treatment (B). Anti-phospho-c-Jun was used to detect phosphorylated c-Jun while anti-c-Jun detected total c-Jun protein.