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Table 1 Surface marker profile of DCs transduced with LVs or MLV vectors.

From: Alteration of T cell immunity by lentiviral transduction of human monocyte-derived dendritic cells

 

Geometrical Mean Fluorescence ± SD

Surface Marker

Mock

Empty LV

LV

MLV

CD11c

48.8 ± 3.2

47.2 ± 1.3

52.3 ± 2.3

55.3 ± 1.1

CD123

13.0 ± 0.4

13.4 ± 0.8

14.9 ± 0.6

15.7 ± 0.1

CD1a

27.3 ± 1.1

27.6 ± 2.9

21.5 ± 0.2*

31.0 ± 0.3

CD40

8.6 ± 0.1

8.9 ± 0.6

8.6 ± 0.1

9.0 ± 0.3

ICAM-1

462.6 ± 57.5

376.5 ± 30.1

179.5 ± 3.4***

498.5 ± 6.9

CD62L

3.3 ± 0.1

3.2 ± 0.03

3.7 ± 0.1

3.3 ± 0.4

CD80 (B7-1)

9.9 ± 0.9

10.6 ± 0.7

9.3 ± 0.2*

11.3 ± 0.4

CD83

5.8 ± 0.3

5.8 ± 0.1

6.4 ± 0.01

6.0 ± 0.3

CD86 (B7-2)

39.6 ± 3.5

39.6 ± 2.5

31.4 ± 0.4*

47.3 ± 1.5

DC-SIGN

62.7 ± 4.5

55.7 ± 0.4

50.6 ± 1.5*

68.6 ± 4.1

HLA-ABC

13.9 ± 1.3

15.8 ± 1.0

14.6 ± 0.3

17.2 ± 0.9

HLA-DR

31.5 ± 0.8

28.6 ± 2.2

26.9 ± 0.4

33.2 ± 1.7

  1. Results are presented as geometrical mean fluorescence after FACS. Asterisks (*) denote significance of difference by Student t-test (*P < 0.05, **P < 0.01, ***P < 0.001).