Table 4 Estimated time of HML-9 elements integration
From: Comprehensive identification and characterization of the HERV-K (HML-9) group in the human genome
Locus | Provirus regions | Divergence from consensus sequence | Mean divergences | T = D/0.2 | Age/million years (gene vs consensus) | Divergence between 2 LTRs | T = D/0.2/2 | Age/million years (LTR vs LTR) | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
gag | pro | pol | env | ||||||||
16p12.3 | chr16 19393581 19402152 | 0.059 | 0.158 | 0.206 | 0.089 | 0.128 | 0.64 | 64.00 | 0.082 | 0.20500 | 20.50000 |
2p12 | chr2 82022660 82031279 | 0.061 | 0.182 | 0.204 | 0.101 | 0.137 | 0.685 | 68.50 | 0.070 | 0.17500 | 17.50000 |
15q21.1 | chr15 45234477 45243073 | 0.051 | 0.126 | 0.206 | 0.099 | 0.121 | 0.6025 | 60.25 | 0.080 | 0.20000 | 20.00000 |
8p11.1 | chr8 43694016 43702583 | 0.091 | 0.177 | 0.231 | 0.121 | 0.155 | 0.775 | 77.50 | 0.107 | 0.26750 | 26.75000 |
13q31.1 | chr13 84869526 84877320 | 0.054 | NA | 0.208 | 0.103 | 0.122 | 0.608333333 | 60.83 | NA | NA | NA |
4q33 | chr4 170126345 170133883 | 0.058 | 0.172 | 0.214 | NA | 0.148 | 0.74 | 74.00 | NA | NA | NA |
6p12.3 | chr6 48873675 48879725 | 0.063 | NA | NA | 0.106 | 0.085 | 0.4225 | 42.25 | 0.110 | 0.27500 | 27.50000 |
Yp11.2 | chrY 9273707 9279611 | 0.114 | NA | NA | 0.139 | 0.127 | 0.6325 | 63.25 | 0.141 | 0.35250 | 35.25000 |
8q24.3 | chr8 145019974 145032719 | NA | NA | 0.513 | 0.093 | 0.303 | 1.515 | 151.50 | NA | NA | NA |
Yq11.223 | chrY 21580120 21585551 | 0.105 | NA | NA | 0.140 | 0.123 | 0.6125 | 61.25 | NA | NA | NA |
19q13.2 | chr19 40954172 40959178 | 0.075 | NA | NA | 0.075 | 0.375 | 37.50 | 0.097 | 0.24250 | 24.25000 | |
Yp11.2 | chrY 8121821 8126768 | NA | NA | NA | 0.125 | 0.125 | 0.625 | 62.50 | 0.157 | 0.39250 | 39.25000 |
Yp11.2 | chrY 8996062 9000755 | NA | NA | NA | 0.133 | 0.133 | 0.665 | 66.50 | NA | NA | NA |
Yq11.222 | chrY:18622534–18626952 | NA | NA | NA | NA | NA | NA | NA | 0.194 | 0.48500 | 48.50000 |
Yq11.223 | chrY 21845475 21850069 | NA | NA | NA | 0.143 | 0.143 | 0.715 | 71.50 | NA | NA | NA |
21q21.1 | chr21 18563368 18566735 | NA | 0.266 | 0.190 | NA | 0.228 | 1.14 | 114.00 | NA | NA | NA |
5q33.3 | chr5 156660448 156663815 | NA | 0.215 | 0.160 | NA | 0.188 | 0.9375 | 93.75 | NA | NA | NA |
1q22 | chr1 155629408 155632775 | NA | 0.212 | 0.156 | NA | 0.184 | 0.92 | 92.00 | NA | NA | NA |
7q36.1 | chr7 150561277 150563994 | NA | NA | NA | 0.197 | 0.197 | 0.985 | 98.50 | NA | NA | NA |
10q24.2 | chr10 99822511 99825532 | NA | NA | 0.169 | NA | 0.169 | 0.845 | 84.50 | NA | NA | NA |