- aPredicted epitope representing the consensus sequence obtained from HIV-1 subtype B. ? denote mix of more than two aa in that position in the HIV data base (https://www.hiv.lanl.gov/content/sequence/QUICK_ALIGNv2/QuickAlign.html)
- bShannon entropy values at population level calculated as described in Methods
- cDate refers to the different time-points sequenced. Samples before and after LVC are separated by a black line
- Aa sequence conservation relative to the HXB2 subtype B consensus is indicated with dashes. Lower case letters indicate a mix of two aa, the consensus and the mutated one