Fig. 3

Antiviral Activities of RPV and RPV analogs against mutants selected by DOR in cell culture. RPV and the RPV analogs were tested against several mutants selected by DOR in cell culture. The IC₅₀ values for RPV and the RPV analogs were measured using a single round infection assay. Error bars represent the standard deviations of independent experiments, n = 4. The IC₅₀ values of the graph are at a maximum value of 100 nM. To better illustrate the lower IC₅₀ values, the Y-axis is broken from 10 to 20 nM and also shown in the corresponding bars