Table 4 Inactivation of isolated HIV particles by WDO-217
Compound | CCID50/ml | |
|---|---|---|
HIV-1 IIIB | HIV-2 ROD | |
No drug | 1 × 106 | 5.4 × 106 |
AZT (3.7 μM) | 1 × 106 | 5.4 × 106 |
Triton X-100 (0.5%) | 0 | 0 |
WDO-217 (0.2 μM) | 5.4 × 106 | 1.6 × 106 |
WDO-217 (1 μM) | 1.6 × 106 | 1 × 106 |
WDO-217 (5 μM) | 1 × 106 | 2.1 × 106 |
WDO-217 (25 μM) | 0 | 0 |
WDO-217 (125 μM) | 0 | 0 |
WDO-217 (625 μM) | 0 | 0 |