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Table 1 Characteristics of HIV-1 subtype B patients included in the analyses for prediction of viral load and CD4 cell count

From: Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients

Characterististics

Subtype B patients (N = 1599)

TDR (N = 151)

Wild-type (N = 1446)

log10 HIV-RNA copies/ml

4.85 (4.32 – 5.35)

4.83 (4.30 – 5.33)

4.86 (4.32 – 5.35)

CD4 cells/mm3

382 (212 – 583)

410 (249 – 582)

377 (209 – 583)

Age, years

35 (29 – 42)

34 (28 – 40)

35 (30 – 42)

Male sex , n (%)

1413 (89%)

137 (91%)

1276 (89%)

Duration of infection, n (%)

   

     < 1 year

541 (34%)

57 (37%)

484 (33%)

     Undefined

1056 (66%)

94 (63%)

962 (67%)

Source of HIV-1exposure, n (%)

   

     Homo/bisexual contact

1016 (65%)

104 (69%)

912 (63%)

     Heterosexual contact

123 (20%)

26 (17%)

290 (20%)

     Intravenous drug use

316 (8%)

8 (5%)

115 (8%)

     Other

142 (9%)

13 (9%)

129 (9%)

Area of origin, n (%)

   

     Western Europe

1147 (72%)

105 (70%)

1042 (72%)

     Eastern Europe & Central Asia

282 (18%)

27 (19%)

255 (18%)

     Other

168 (10%)

19 (11%)

149 (10%)

  1. Patient characteristics are shown for the subtype B study dataset (N = 1599), including patients with genotypic evidence of transmitted drug resistance (TDR) and patients without genotypic evidence of transmitted drug resistance (wild-type). Data are expressed as median values accompanied by interquartile ranges, or as number of patients accompanied by proportion of the subtype B dataset (%).