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Table 2 HTLV-2 p28-interacting host proteins

From: Comparative host protein interactions with HTLV-1 p30 and HTLV-2 p28: insights into difference in pathobiology of human retroviruses

Name of the protein

Molecular function

Unweighted spectrum count

% coverage

Heterogeneous nuclear ribonucleoprotein H1

mRNA processing

8

4.3

Heterogeneous nuclear ribonucleoprotein K

mRNA processing

6

5.2

Serine/threonine-protein phosphatase 6 catalytic subunit

Protein phosphatase

5

8.9

Serine/threonine-protein phosphatase 6 regulatory subunit 3

Phosphatase regulator

3

5.1

Protein arginine methyl transferase 5

Arginine methylation

3

6.4

Poly (A) binding protein 1 or 4

Poly (A) RNA binding

3

12

Inorganic pyrophosphatase

Inorganic diphosphatase activity

2

9

Peroxiredoxin-2

Antioxidant

2

15

60 S ribosomal protein L29

Component of ribosome

2

9.3

60 S ribosomal protein L8

Component of ribosome

2

5.2

Nucleolin

RNA,DNA and nucleotide binding

1

1.4

Glutathione S-transferase P

Glutathione transferase activity

1

13

Serine/threonine-protein phosphatase 2A regulatory subunit B

Phosphatase regulator

1

3.3

Nascent polypeptide-associated complex subunit alpha-2

Protein transport

1

7

Cyclic nucleotide gated channel 3

Predicted ion channel activity

1

1.7

Obg-like ATPase 1

Predicted ATP hydrolysis

1

3.8

Elongation factor Tu (Mitochondrial)

Translation elongation

1

2.9

Triosephosphate isomerase

Phosphate isomerase

1

9.6

Heparan sulfate proteoglycan 2

Predicted extracellular matrix binding

1

0.34

Heterogeneous nuclear ribonucleoprotein F

RNA processing

1

4.1

40 S ribosomal protein S8

Component of ribosome

1

5.4

Chaperonin 10

Protein folding

1

11

  1. List of host proteins identified by shotgun proteomics that co-purified with p28 after eliminating non-specific and contaminating proteins. The molecular processes in which these proteins are involved are mentioned next to the proteins. The number of unweighted spectrum counts and percentage coverage of each protein are indicated.