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Figure 1 | Retrovirology

Figure 1

From: Relationships of PBMC microRNA expression, plasma viral load, and CD4+ T-cell count in HIV-1-infected elite suppressors and viremic patients

Figure 1

Hierarchical clustering of NanoString miRNA profiling results. NanoString miRNA profiling results for PBMC RNA of eight control (C, blue), seven elite suppressor (ES, red), and six viremic (V, green) donors were log-2 transformed and quantile normalized. Values at least one standard deviation above background were included. Data were filtered using one-way analysis of variance (ANOVA, A, C, D) or t-tests with Welch approximation (B). Features with significant difference at p < 0.05 (A, about 50 features) or p < 0.01 (about 20 features, B-D) were used for hierarchical clustering of samples by Euclidean distance or Pearson correlation and average linkage, as indicated. Additional tests using complete linkage were performed with comparable outcome (not shown).

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Retrovirology

ISSN: 1742-4690

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