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Table 1 Characteristics of SIVmac251-infected rhesus macaques

From: Stable multi-infection of splenocytes during SIV infection - the basis for continuous recombination

Monkey

Duration of infection (weeks)

Absolute CD4+ T cells (cell/ÎĽl)

Plasma viral load (SIV-RNA/ml)

Number of infected cells counted

Relative SIV copy number distribution

     

1 copy

2 copies

3 copies

8310 (I)

0

804

nd

-

-

-

-

8326 (I)

2

1980

nd

83

0.77

0.20

0.02

7783 (C)

2

471

nd

125

0.69

0.31

-

8152 (I)

4

nd

nd

28

0.82

0.18

-

7793 (C)

7

471

nd

122

0.80

0.20

-

8179 (C)

12

252

7.7 Ă— 103

52

0.73

0.27

-

1740 (I, A)

13

131

2.3 Ă— 108

77

0.73

0.27

-

7785 (C)

17

910

nd

45

0.67

0.33

-

8159 (I)

18

545

nd

163

0.72

0.28

-

7786 (C)

19

840

nd

111

0.73

0.27

-

1778 (I, A)

29

571

3, 1 Ă— 106

41

0.49

0.51

-

1718, (I, A)

51

54

2.6 Ă— 105

93

0.68

0.29

0.03

  1. Relative SIV copy number distribution including the number of infected cells counted and some characteristics of the SIV infection are given for all monkeys studied. The determined copy numbers are the result of 2 to 4 independent FISH experiments. The standard deviation of individual copy number counts was less than 10%. Around 200 to 300 non-infected control cells were inspected in each FISH experiment. I = Rhesus macaques of Indian origin; C = Rhesus macaques of Chinese origin; A = AIDS state.