The HR2 polymorphism N140I in the HIV-1 gp41 combined with the HR1 V38A mutation is associated with a less cytopathic phenotype

Table 1 Characteristics of the three patients receiving an enfuvirtide-containing salvage therapy when samples were collected

Patient^a	Sample	Weeks on ENF treatment	Plasma viral load (copies/mL)	CD4⁺ cell count (cells/μl)	No. of expression plasmids constructed
140N (9)	140N	0	366357	491	5
	V38A 140N	24	8536	700	8
N140T (10)	N140T	0	141497	13	10
	V38A N140T	4	332794	13	9
N140I (1)	N140I	0	33470	145	10
	V38A N140I	12	10806	150	6

ISSN: 1742-4690