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Figure 1 | Retrovirology

Figure 1

From: The HR2 polymorphism N140I in the HIV-1 gp41 combined with the HR1 V38A mutation is associated with a less cytopathic phenotype

Figure 1

The sequence alignment of the gp41 gene from the recombinant envelope-expressing plasmids constructed from patient samples. The alignment of the gp41 ectodomain sequence (HR1 and HR2 domains) from the selected recombinant plasmids derived from three patients who failed an ENF-based treatment and carried a V38A mutation (HR1 box) with the amino acid I, N or T at position 140 (HR2 box). The Cav-1 binding domain in the HR2 region is highlighted.

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