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Figure 5 | Retrovirology

Figure 5

From: Inhibition of HIV-1 infection by TNPO3 depletion is determined by capsid and detectable after viral cDNA enters the nucleus

Figure 5

Strategy for detecting cDNA from HIV-1 reporter virus after challenge of cells that had been previously transduced with HIV-1-based, lentivirus KD and rescue vectors. Schematic diagram showing methods of detection for HIV-1 late RT products (A), 2-LTR circles (B) and provirus (C) in KD cell lines. Identification of nascent cDNA is made possible by the presence of a loxP sequence engineered within a region of the 3'LTR U3 that is dispensable for retrotransposition.

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Retrovirology

ISSN: 1742-4690

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