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Figure 4 | Retrovirology

Figure 4

From: Increased APOBEC3G and APOBEC3F expression is associated with low viral load and prolonged survival in simian immunodeficiency virus infected rhesus monkeys

Figure 4

mRNA levels of interferon-stimulated genes (ISGs) in uninfected and SIV-infected macaques. Upper panels show relative MxA (A) and IP-10 (B) mRNA levels in PBMC of uninfected (triangles) and SIV-infected animals with (diamonds) or without (circles) AIDS symptoms. Each data point represents one individual animal. Relative ISG transcription levels are shown in copy numbers per 100 copies of GAPDH. Horizontal lines within the clusters are depicting the median. P values were calculated using the Kruskal-Wallis test with Dunn's multiple comparison analysis (**p < 0.001; ***p < 0.0001). Lower panels display the relationship between MxA (C) and IP-10 mRNA levels (D) and plasma viral load in PBMC. Viral load is depicted as log-transformed RNA copies per millilitre (ml) plasma. asymp., asymptomatic r; Spearman's correlation coefficient; line shows nonlinear regression p, P value.

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Retrovirology

ISSN: 1742-4690

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