From: HIV-1 protease inhibitor mutations affect the development of HIV-1 resistance to the maturation inhibitor bevirimat
Virus
Fold resistance
bevirimat
-
V362I
A364V
S368N
V370A
HXB2
2.8
> 150
6.6
PR-1 (20R-36I-54V-63P-71I-82T)
0.6
2.1
6.0
PR-2 (431V-10I-13V-36I-46I-54V-62V-63P-71T-82A-90M-93L)