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Table 2 Amino acid substitutions of HIV-2 IN at RAL failure

From: G140S/Q148R and N155H mutations render HIV-2 Integrase resistant to Raltegravir whereas Y143C does not

Sequence

Residue

 

92

97

143

155

EHO (B)

E

T

Y

N

Pat. T1

A

A

-

H

Pat. T2

Q

-

C

-

 

140

148

  

ROD (A)

G

Q

  

Pat. T3

S

R

  

Pat. T4

S

R

  

Pat.T5

A

R

  

Pat. T6

-

R

  

Pat. T7

A

R

  
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Retrovirology

ISSN: 1742-4690

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