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Figure 1 | Retrovirology

Figure 1

From: Cysteine 95 and other residues influence the regulatory effects of Histidine 69 mutations on Human Immunodeficiency Virus Type 1 protease autoprocessing

Figure 1

Schematic illustration of constructs with or without H69E mutation. (A) Organization of structural domains in the Gag and Gag-PR polyproteins: MA, matrix; CA, capsid (p24); NC, nucleocapsid; p6, late domain protein; TFR, transframe region; PR, protease. Straight arrows indicate the protease cleavage sites. Amino acids that are different between NL4-3 and wtpseproteases are denoted. (B) Schematic summary on H69E containing mutants and their relative Gag processing efficiencies.

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Retrovirology

ISSN: 1742-4690

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