Frequent CXCR4 tropism of HIV-1 subtype A and CRF02_AG during late-stage disease - indication of an evolving epidemic in West Africa

Table 2 Clinical parameters, HIV-1 subtype and HIV-1 tropism of the 29 analyzed study subjects.

Patient No.	Sex¹	CD4%²	CD4tot³	CDC⁴	WHO⁵	Subtype	Tropism	Sample year
DL1996H	M	5	157	B	3	CRF02_AG	R5X4	2000
DL2089J	M	9	59	B	3	CRF02_AG	R5X4	2003
DL2096F	M	5	22	C	4	C	N/A⁶	2003
DL2249I	M	2	21	C	4	CRF02_AG	R5X4	2004
DL2339E	M	12	178	B	3	CRF02_AG	R5X4	2003
DL2365K	M	9	133	B	3	A3	R5	2006
DL2391G	M	5	N/A⁶	B	2	CRF02_AG	R5	2000
DL2401M	M	11	141	B	3	CRF02_AG	R5X4	2004
DL2713H	M	N/A⁶	N/A⁶	B	2	CRF02_AG	R5X4	2007
DL2846I	F	N/A⁶	N/A⁶	B	3	A3	R5X4	2005
DL2853E	M	11	137	A	1	CRF02_AG	R5	1998
DL2920H	M	11	126	B	3	CRF02_AG	X4	2004
DL3018H	M	N/A⁶	N/A⁶	B	3	A3	R5X4	2006
DL3037E	M	3	74	B	3	CRF02_AG	R5X4	2005
DL3039G	F	7	148	A	2	CRF02_AG	R5X4	2006
DL3071H	F	20	123	B	3	A3	R5X4	2005
DL3087E	M	4	62	B	2	CRF02_AG	R5X4	2001
DL3098I	F	14	426	N/A⁶	N/A⁶	CRF02_AG	R5X4	2007
DL3169F	M	9	315	B	3	CRF02_AG	R5X4	2004
DL3170F	M	8	65	B	2	CRF02_AG	R5X4	2000
DL3234J	M	10	216	A	2	CRF02_AG	R5X4	2006
DL3312E	M	2	36	C	4	CRF02_AG	R5X4	1998
DL3633G	F	8	112	C	4	CRF02_AG	R5X4	2003
DL3721C	M	11	257	A	1	CRF02_AG	R5X4	1997
DL3733G	M	19	137	B	3	CRF02_AG	R5X4	2004
DL4248G	F	13	159	B	3	A3	R5	2005
DL4477D	M	14	141	B	3	CRF02_AG	R5	2001
DL4525G	M	13	372	B	3	A3	R5	2006
DL4632E	F	9	77	B	3	CRF02_AG	R5X4	2003

¹M = male, F = female
²CD4+ T cell percentage among all T cells
³CD4+ T cell count per microliter among all T cells
⁴Clinical category of the patient, as defined by the CDC, at the sample time point
⁵Clinical category of the patient, as defined by the WHO, at the sample time point
⁶N/A = not analyzed
⁷Sample included in the study based on previous examinations of CD4+ T cell count and percentage

ISSN: 1742-4690