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Table 5 Host restriction factors that inhibit replication of gammaretroviruses.

From: The mouse "xenotropic" gammaretroviruses and their XPR1 receptor

 

Restriction*

Restriction Factor

X-MLV

P-MLV

XMRV

E-MLV

Xpr1

+

+

+

-

Entry: glycosylation

+

-

-

+

Lvif

+

+

?

-

ERV interference

?

+ (Rmcf genes)

?

+(Fv4)

Fv1

+

+

+

+

Apobec3

-?

+?

+

+

Tetherin/BST2

?

?

+

+

  1. *+, infectious virus known to be inhibited; determination of Apobec3 restriction of X/P-MLVs based on mutational patterns found in ERVs [25].