Volume 6 Supplement 2

Frontiers of Retrovirology: Complex retroviruses, retroelements and their hosts

Open Access

Novel cellular processes that regulate post-transcriptional expression of HIV-1 transcripts

  • Kuan-Teh Jeang1
Retrovirology20096(Suppl 2):I15

DOI: 10.1186/1742-4690-6-S2-I15

Published: 24 September 2009

5'-capping is an early mRNA modification that has important consequences for downstream events in gene expression such as pre-mRNA synthesis and splicing, mRNA cytoplasmic transport, translation, and mRNA turnover. The role of RNA-capping in post-transcriptional regulation of HIV-1 expression has not been examined in detail. Here, we will present data on the roles played by cellular proteins and HIV-1 RNA capping on post-transcriptional expression of viral RNAs.

Authors’ Affiliations

(1)
National Institutes of Health

Copyright

© Jeang; licensee BioMed Central Ltd. 2009

This article is published under license to BioMed Central Ltd.

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