Table 3 Amino acid inter-species, inter-group, inter-subtype, and intra-subtype divergence among protease, RT, and integrase sequences
Divergence | Protease | RT | Integrase |
|---|---|---|---|
Inter-species | Â | Â | Â |
HIV-1 (789) vs HIV-2 (26) | 0.51 ± 0.03 | 0.40 ± 0.04 | 0.40 ± 0.02 |
Inter-group | Â | Â | Â |
group M (764) vs O (21) | 0.29 ± 0.02 | 0.22 ± 0.01 | 0.18 ± 0.01 |
group M (764) vs N (4) | 0.21 ± 0.02 | 0.14 ± 0.01 | 0.11 ± 0.01 |
group O (21) vs N (4) | 0.30 ± 0.02 | 0.21 ± 0.01 | 0.18 ± 0.01 |
Inter-subtype | Â | Â | Â |
Subtype A (71) vs B (145) | 0.11 ± 0.03 | 0.10 ± 0.01 | 0.07 ± 0.01 |
Subtype A (71) vs C (337) | 0.10 ± 0.03 | 0.09 ± 0.01 | 0.07 ± 0.01 |
Subtype B (145) vs C (337) | 0.11 ± 0.02 | 0.09 ± 0.01 | 0.07 ± 0.01 |
Intra-subtype | Â | Â | Â |
Subtype A (71) | 0.05 ± 0.02 | 0.07 ± 0.02 | 0.05 ± 0.01 |
Subtype B (145) | 0.07 ± 0.03 | 0.06 ± 0.01 | 0.05 ± 0.02 |
Subtype C (337) | 0.06 ± 0.03 | 0.06 ± 0.01 | 0.04 ± 0.01 |