Inhibitor/Antibody | Target of reagent | Stage of entry blocked3. | Correlation with Macrophage-tropism (p Values) |
---|---|---|---|
Q4120 | CD4 | env: CD4 interactions | <0.0001** |
sCD4 | gp120, CD4bs | env: CD4 interactions | <0.0001** |
PRO 542 (IgG-CD4) | gp120, CD4bs | env: CD4 interactions | <0.0001** |
BMS-378806 | gp120, CD4bs channel1. | env: CD4 interactions | 0.0002** |
b12 | gp120, overlapping CD4bs2. | Â | 0.6843 |
TAK779 | CCR5 | env: CCR5 interactions | 0.7964 |
SCH350581 | CCR5 | env: CCR5 interactions | 0.7587 |
2D7 | CCR5 | env: CCR5 interactions | Â |
2G12 | gp120 glycan | env: CCR5 interactions | 0.0138* |
T20 | gp41 conformational changes | gp41 conformational changes | 0.7061 |
2F5 | gp41 membrane proximal region | gp41 conformational changes4. | 0.3741 |
4E10 | gp41 membrane proximal region | gp41 conformational changes4. | 0.3502 |