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Figure 6 | Retrovirology

Figure 6

From: Expression of parathyroid hormone-related protein during immortalization of human peripheral blood mononuclear cells by HTLV-1: Implications for transformation

Figure 6

HTLV-1 infection or over-expression of Rex alone up-regulated PTHrP expression. Relative luciferase activity in 293T cells transfected with either pGL2 or pGL2 PTHrP-P2/P3 Luc constructs alone or with expression plasmids for HTLV-1 (ACH), p12, p13, p30, HBZ, Rex and Tax. The quantity of the expression plasmid is indicated in μg. Bars represent the mean ± SD of three independent samples. Relative Luc/Gal units were significantly different across groups (p = 0.0002). After adjusting for multiple times of comparison, P2/P3Luc+Rex group and P2/P3Luc+ACH group had significantly greater relative Luc/Gal units than the P2/P3Luc group (p = 0.0006, p = 0.0012, respectively; indicated by asterisks in the figure).

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Retrovirology

ISSN: 1742-4690

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