Table 2 Frequencies of resistance mutations detected in cloned PBMCs^a

PR

10

16

35

36

37

41

46

48

54

60

63

69

77

82

90

HxB2

L

G

E

M

S

M

G

I

D

L

H

V

V

L

Clones

I 100%

E 100%

D 26.0%

V 1%

T 99.0%

K 72.9%

I 42.7%

V 100%

V 54.2%

E 100%

P 99.0%

Y 26.0%

I 100%

A 54.2%

M 45.8%

T 1%

I 1.0%

L 55.2%

H 1.0%

I 1%

S 1.0%

RT

41

44

69

74

98

101

102

108

118

181

184

190

208

210

211

214

215

219

283

HxB2

M

E

T

L

A

K

K

V

V

Y

M

G

H

L

R

L

T

K

L

Clones

L

A

N

V

G

E

Q

I

I

C

V

A

Y

W

D

F

Y

R

I

100%

97.9%

12.5%

2.1%

100%

18.75%

97.9%

19.8%

100%

45.8%

81.2%

45.8%

100%

100%

97.9%

100%

100%

47.9%

100%

T

A

Q

R

T

E

2.1%

1.0%

1.0%

21.%

1.0%

2.1%