Immunotherapy with internally inactivated virus loaded dendritic cells boosts cellular immunity but does not affect feline immunodeficiency virus infection course

Table 1 Numbers of FIV-DCs inoculated per immunization into each experimental cat.

Cat ID	Years of infection	FIV-binding antibody titer^a	FIV-DCs reinoculated (× 10⁶)
			Inoculum
			1st	2nd	3rd	Total
DB	7	3200	2	2	2	6
DC	7	3200	-	0.5	1.5	2
EM	3	800	3	3	1	7
EQ	3	3200	3	2	3	8
S6	7	6400	0.5	2	0.5	3
S8	7	3200	1.5	1	1	3.5
S9	7	6400	1	-	0.5	1.5
S14	7	800	1.5	0.5	0.5	2.5
S15	7	800	0.5	2	1	3.5
GY15	1	400	1.5	2.5	3	7
HB17	1	400	4.5	2	2	8.5

^a Titers are expressed as reciprocals of the highest serum dilutions that gave optical density readings at least threefold higher than the average values obtained with 10 control FIV-negative sera plus 3 times the standard deviation. Titers remained constant throughout the observation period.
^b FIV-MDCs were generated from each individual cat as described in the text. On the days of treatment, they were harvested, counted and reinjected into the corresponding donor cats. Numbers represent live cells, as evaluated by trypan blue exclusion.

ISSN: 1742-4690