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Figure 8 | Retrovirology

Figure 8

From: Distinct efficacy of HIV-1 entry inhibitors to prevent cell-to-cell transfer of R5 and X4 viruses across a human placental trophoblast barrier in a reconstitution model in vitro

Figure 8

The fusion inhibitor T20 inhibits viral passage across the BeWo monolayer in contact with HIV-1/LAI infected CD4+ T cells. The experiment was designed as described for figure 3, except that purified CD4 positive T cells were used as effector cells, instead of whole PBMCs, for infection with HIV-1 LAI. The figure shows a dose-dependent inhibition of the interaction between BeWo-CD4 negative target cells and CD4+ T cells infected with HIV-1/LAI.

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Retrovirology

ISSN: 1742-4690

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