Figure 1From: Role of receptor polymorphism and glycosylation in syncytium induction and host range variation of ecotropic mouse gammaretroviruses(A) Comparison of the deduced amino acid sequences of the third extracellullar loop of the CAT-1 receptor. Glycosylation sites are underlined. Sequences for mCAT-1 (NIH 3T3) and dCAT-1 (M. dunni) were previously determined (GenBank accession no. M26687, [6]). dCAT-1-g was generated by mutagenesis. (B) Expression of HA-tagged CAT-1 genes in various cell lines. a, Tb-1-Lu cells with mCAT-1; b, Tb-1-Lu with dCAT-1; c, MA139 cells with mCAT-1, d and e, MA139 with dCAT-1; f, M. dunni with m-CAT-1. Cell lysates were electrophoresed on 8% (right panel) or 10% gels. Molecular weight markers are given for each panel.Back to article page